| 4. Ronde | 28.08.2021 | US Saint-Malo | - | EA Guingamp B | 0:2 | ||||
| 7. Ronde | 18.09.2021 | EA Guingamp B | - | Blois Foot 41 | 2:3 | ||||
| 8. Ronde | 25.09.2021 | FC Lorient B | - | EA Guingamp B | 3:0 | ||||
| 9. Ronde | 09.10.2021 | EA Guingamp B | - | SM Caen B | 1:1 | ||||
| 10. Ronde | 23.10.2021 | EA Guingamp B | - | AS Poissy | 1:1 | ||||
| 11. Ronde | 06.11.2021 | C'Chartres Football | - | EA Guingamp B | 1:2 | ||||
| 12. Ronde | 20.11.2021 | EA Guingamp B | - | Châteaubriant Voltigeurs | 2:3 | ||||
| 14. Ronde | 11.12.2021 | EA Guingamp B | - | US Granvillaise | 1:0 |
Frankrijk