| 3. Ronde | 26.09.2021 | Progreso | - | Cerrito | 0:1 | ||||
| 4. Ronde | 02.10.2021 | Cerrito | - | Sud América | 2:0 | ||||
| 5. Ronde | 11.10.2021 | Plaza Colonia | - | Cerrito | 3:3 | ||||
| 6. Ronde | 17.10.2021 | Cerrito | - | Fénix | 2:4 |  |
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| 7. Ronde | 21.10.2021 | Boston River | - | Cerrito | 3:2 | |
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| 8. Ronde | 24.10.2021 | Cerrito | - | Montevideo Wanderers | 2:2 | ||||
| 9. Ronde | 29.10.2021 | Rentistas | - | Cerrito | 1:2 | ||||
| 10. Ronde | 05.11.2021 | Cerrito | - | Peñarol | 1:3 | |
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| 11. Ronde | 07.11.2021 | Cerrito | - | Montevideo City Torque | 0:2 | |
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| 13. Ronde | 19.11.2021 | Nacional | - | Cerrito | 1:0 | ||||
| 14. Ronde | 25.11.2021 | Deportivo Maldonado | - | Cerrito | 0:1 | |
Uruguay
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