| 4. Ronde | 04.02.2021 | River Plate | - | Danubio | 0:4 | ||||
| 6. Ronde | 11.02.2021 | River Plate | - | Boston River | 3:1 | ||||
| 7. Ronde | 14.02.2021 | Deportivo Maldonado | - | River Plate | 1:2 | ||||
| 8. Ronde | 17.02.2021 | River Plate | - | Rentistas | 1:1 | ||||
| 9. Ronde | 20.02.2021 | River Plate | - | Cerro Largo | 2:0 |  |
|||
| 11. Ronde | 07.03.2021 | Peñarol | - | River Plate | 2:0 | |
Uruguay