| 5. Ronde | 03.10.2021 | Anorthosis Famagusta | - | APOEL Nicosia | 2:1 | ||||
| 7. Ronde | 25.10.2021 | Anorthosis Famagusta | - | AEK Larnaca | 1:2 | ||||
| 9. Ronde | 07.11.2021 | Anorthosis Famagusta | - | Paphos FC | 1:0 | ||||
| 11. Ronde | 29.11.2021 | Anorthosis Famagusta | - | Apollon Limassol | 1:1 | ||||
| 12. Ronde | 04.12.2021 | Anorthosis Famagusta | - | PAEEK | 2:3 |  |
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| 1. Ronde | 22.12.2021 | PAEEK | - | Anorthosis Famagusta | 0:2 | ||||
| 17. Ronde | 16.01.2022 | Anorthosis Famagusta | - | AEL Limassol | 2:1 | ||||
| 18. Ronde | 24.01.2022 | AEK Larnaca | - | Anorthosis Famagusta | 1:1 | ||||
| 19. Ronde | 29.01.2022 | Anorthosis Famagusta | - | Omonia Nikosia | 1:1 | |
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| 20. Ronde | 06.02.2022 | Paphos FC | - | Anorthosis Famagusta | 1:1 | ||||
| 15. Ronde | 10.02.2022 | Anorthosis Famagusta | - | Aris Limassol | 3:1 | ||||
| 16. Ronde | 17.02.2022 | APOEL Nicosia | - | Anorthosis Famagusta | 0:2 | ||||
| 22. Ronde | 26.02.2022 | Apollon Limassol | - | Anorthosis Famagusta | 2:2 |
Cyprus