| 1. Ronde | 05.09.2021 | Peña Deportiva | - | SD Ejea | 1:0 | ||||
| 2. Ronde | 12.09.2021 | SD Huesca B | - | Peña Deportiva | 1:1 |  |
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| 3. Ronde | 19.09.2021 | Peña Deportiva | - | CD Brea | 3:0 | ||||
| 4. Ronde | 26.09.2021 | CD Numancia | - | Peña Deportiva | 2:1 | ||||
| 5. Ronde | 03.10.2021 | Peña Deportiva | - | AE Prat | 1:0 | ||||
| 6. Ronde | 10.10.2021 | CF Badalona | - | Peña Deportiva | 0:1 | ||||
| 8. Ronde | 24.10.2021 | CE Andratx | - | Peña Deportiva | 4:3 |  |
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| 9. Ronde | 31.10.2021 | Peña Deportiva | - | CD Ibiza | 0:0 | ||||
| 10. Ronde | 07.11.2021 | SD Tarazona | - | Peña Deportiva | 1:0 | ||||
| 11. Ronde | 14.11.2021 | Peña Deportiva | - | CD Teruel | 2:2 | |
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| 12. Ronde | 21.11.2021 | CD Ebro | - | Peña Deportiva | 1:1 | ||||
| 13. Ronde | 28.11.2021 | Peña Deportiva | - | Lleida Esportiu | 2:1 | ||||
| 14. Ronde | 05.12.2021 | Espanyol B | - | Peña Deportiva | 0:3 | ||||
| 15. Ronde | 12.12.2021 | Peña Deportiva | - | Cerdanyola FC | 1:1 | |
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| 16. Ronde | 19.12.2021 | Terrassa FC | - | Peña Deportiva | 1:2 | |
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| 17. Ronde | 09.01.2022 | Peña Deportiva | - | SD Formentera | 0:3 |
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