| 2. Ronde | 30.10.2021 | ENPPI | - | Al Mokawloon | 3:2 |  |
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| 3. Ronde | 04.11.2021 | Al Mokawloon | - | Tala'ea El Gaish SC | 1:1 | ||||
| 4. Ronde | 19.11.2021 | Al Ahly SC | - | Al Mokawloon | 1:0 | ||||
| 5. Ronde | 23.11.2021 | Al Mokawloon | - | Ismaily | 1:1 | |
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| 6. Ronde | 26.11.2021 | National Bank SC | - | Al Mokawloon | 2:1 | ||||
| 7. Ronde | 21.12.2021 | Al Mokawloon | - | Zamalek | 1:2 | |
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| 9. Ronde | 15.02.2022 | Ghazl Al Mehalla | - | Al Mokawloon | 1:1 | ||||
| 10. Ronde | 21.02.2022 | Al Mokawloon | - | Smouha Sporting Club | 0:0 | ||||
| 11. Ronde | 25.02.2022 | Future FC | - | Al Mokawloon | 1:0 | ||||
| 12. Ronde | 04.03.2022 | Al Mokawloon | - | Pyramids FC | 0:2 | ||||
| 19. Ronde | 15.05.2022 | Al Mokawloon | - | ENPPI | 2:2 | ||||
| 20. Ronde | 21.05.2022 | Tala'ea El Gaish SC | - | Al Mokawloon | 1:0 | ||||
| 23. Ronde | 28.06.2022 | Al Mokawloon | - | National Bank SC | 1:1 | ||||
| 26. Ronde | 22.07.2022 | Al Mokawloon | - | Ghazl Al Mehalla | 1:0 | |
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| 27. Ronde | 27.07.2022 | Smouha Sporting Club | - | Al Mokawloon | 1:1 | ||||
| 21. Ronde | 30.07.2022 | Al Mokawloon | - | Al Ahly SC | 0:0 | ||||
| 28. Ronde | 02.08.2022 | Al Mokawloon | - | Future FC | 0:1 | ||||
| 29. Ronde | 06.08.2022 | Pyramids FC | - | Al Mokawloon | 1:0 |
Egypte