| 4. Ronde | 11.09.2021 | Lille OSC [A-jun] | - | Entente Feignies Aulnoye [A-jun] | 3:1 | ||||
| 8. Ronde | 10.10.2021 | Lille OSC [A-jun] | - | Havre AC [A-jun] | 1:1 | ||||
| 10. Ronde | 24.10.2021 | Lille OSC [A-jun] | - | FC Chambly [A-jun] | 0:0 | ||||
| 11. Ronde | 14.11.2021 | Valenciennes FC [A-jun] | - | Lille OSC [A-jun] | 2:1 | ||||
| 15. Ronde | 16.01.2022 | Évreux FC 27 [A-jun] | - | Lille OSC [A-jun] | 2:0 | ||||
| 17. Ronde | 06.02.2022 | Lille OSC [A-jun] | - | Amiens SC [A-jun] | 0:3 | ||||
| 18. Ronde | 13.02.2022 | JA Drancy [A-jun] | - | Lille OSC [A-jun] | 4:3 | ||||
| 19. Ronde | 06.03.2022 | Lille OSC [A-jun] | - | Paris Saint-Germain [A-jun] | 1:1 | ||||
| 21. Ronde | 27.03.2022 | Lille OSC [A-jun] | - | SM Caen [A-jun] | 5:1 | ||||
| 22. Ronde | 03.04.2022 | FC Chambly [A-jun] | - | Lille OSC [A-jun] | 1:1 | ||||
| 23. Ronde | 10.04.2022 | Lille OSC [A-jun] | - | Valenciennes FC [A-jun] | 0:1 |
Frankrijk