| 15. Ronde | 23.10.2021 | FC Sheriff | - | FC Bălţi | 2:0 | ||||
| 6. Ronde | 01.03.2022 | FC Sheriff | - | FC Milsami | 1:0 | ||||
| 7. Ronde | 05.03.2022 | FC Sheriff | - | FC Sfîntul Gheorghe | 2:0 | ||||
| 21. Ronde | 19.03.2022 | FC Sfîntul Gheorghe | - | FC Sheriff | 0:3 | ||||
| 22. Ronde | 03.04.2022 | FC Bălţi | - | FC Sheriff | 0:3 |  |
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| 23. Ronde | 08.04.2022 | FC Sheriff | - | CS Petrocub | 1:0 | ||||
| 24. Ronde | 16.04.2022 | FC Zimbru | - | FC Sheriff | 1:1 | ||||
| 26. Ronde | 29.04.2022 | Dinamo-Auto | - | FC Sheriff | 0:3 | |
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| 27. Ronde | 07.05.2022 | FC Milsami | - | FC Sheriff | 1:1 | ||||
| 28. Ronde | 14.05.2022 | FC Sheriff | - | FC Sfîntul Gheorghe | 2:0 |
Mali