| 1. Ronde | 16.08.2015 | Juventud de Las Piedras | - | Danubio | 0:2 | ||||
| 4. Ronde | 06.09.2015 | Danubio | - | Defensor Sporting | 2:3 | ||||
| 5. Ronde | 12.09.2015 | Fénix | - | Danubio | 2:1 |  |
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| 6. Ronde | 19.09.2015 | Danubio | - | Sud América | 1:1 | ||||
| 7. Ronde | 26.09.2015 | Racing | - | Danubio | 0:0 |  |
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| 9. Ronde | 18.10.2015 | River Plate | - | Danubio | 2:1 | |
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| 10. Ronde | 24.10.2015 | Rentistas | - | Danubio | 0:2 | ||||
| 11. Ronde | 01.11.2015 | Danubio | - | Liverpool | 4:0 | ||||
| 12. Ronde | 07.11.2015 | Villa Teresa | - | Danubio | 0:1 | |
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| 13. Ronde | 21.11.2015 | Danubio | - | Nacional | 2:0 | ||||
| 14. Ronde | 29.11.2015 | Montevideo Wanderers | - | Danubio | 0:0 | |
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| 15. Ronde | 05.12.2015 | Danubio | - | Plaza Colonia | 2:2 |
Uruguay