| 3. Ronde | 07.08.2021 | FC Sion | - | BSC Young Boys | 1:0 | ||||
| 4. Ronde | 21.08.2021 | FC St. Gallen | - | FC Sion | 1:1 | ||||
| 5. Ronde | 28.08.2021 | FC Sion | - | FC Lugano | 3:2 | ||||
| 6. Ronde | 12.09.2021 | FC Lausanne-Sport | - | FC Sion | 1:1 | ||||
| 7. Ronde | 23.09.2021 | FC Sion | - | FC Luzern | 1:1 |  |
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| 8. Ronde | 26.09.2021 | Grasshopper Club Zürich | - | FC Sion | 3:1 | ||||
| 9. Ronde | 03.10.2021 | FC Zürich | - | FC Sion | 6:2 | |
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| 10. Ronde | 17.10.2021 | FC Sion | - | FC Basel 1893 | 0:1 | ||||
| 11. Ronde | 24.10.2021 | Servette FC | - | FC Sion | 1:2 | ||||
| 12. Ronde | 31.10.2021 | FC Sion | - | Grasshopper Club Zürich | 1:3 | ||||
| 13. Ronde | 06.11.2021 | FC Luzern | - | FC Sion | 0:1 | ||||
| 19. Ronde | 30.01.2022 | FC Sion | - | Grasshopper Club Zürich | 2:0 | |
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| 20. Ronde | 06.02.2022 | FC Basel 1893 | - | FC Sion | 3:3 | ||||
| 21. Ronde | 13.02.2022 | FC Luzern | - | FC Sion | 1:0 | |
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| 27. Ronde | 20.03.2022 | Servette FC | - | FC Sion | 2:1 | ||||
| 28. Ronde | 02.04.2022 | FC Sion | - | FC St. Gallen | 0:3 | ||||
| 32. Ronde | 01.05.2022 | FC Sion | - | BSC Young Boys | 1:2 | ||||
| 33. Ronde | 08.05.2022 | Grasshopper Club Zürich | - | FC Sion | 0:1 | ||||
| 34. Ronde | 11.05.2022 | FC Sion | - | FC Luzern | 1:3 | ||||
| 36. Ronde | 22.05.2022 | FC Sion | - | Servette FC | 3:3 |
Guadeloupe
Frankrijk