| 1. Ronde | 30.01.2010 | Tacuary | - | Cerro Porteño | 1:2 |  |
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| 4. Ronde | 17.02.2010 | Guaraní | - | Tacuary | 5:2 | ||||
| 5. Ronde | 21.02.2010 | Tacuary | - | Club Rubio Ñu | 0:1 |  |
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| 6. Ronde | 28.02.2010 | Tacuary | - | Sportivo Trinidense | 2:0 | |
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| 7. Ronde | 06.03.2010 | Sportivo Luqueño | - | Tacuary | 3:3 | ||||
| 8. Ronde | 12.03.2010 | Tacuary | - | Sol de América | 1:1 | ||||
| 10. Ronde | 21.03.2010 | Tacuary | - | 3 de Febrero | 3:0 | ||||
| 9. Ronde | 24.03.2010 | Club Nacional | - | Tacuary | 4:0 | ||||
| 11. Ronde | 28.03.2010 | Sport Colombia | - | Tacuary | 0:0 | ||||
| 12. Ronde | 05.04.2010 | Cerro Porteño | - | Tacuary | 1:0 | |
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| 13. Ronde | 10.04.2010 | Tacuary | - | Club Olimpia | 0:4 | ||||
| 15. Ronde | 18.04.2010 | Tacuary | - | Guaraní | 1:4 | ||||
| 19. Ronde | 12.05.2010 | Sol de América | - | Tacuary | 1:0 | ||||
| 20. Ronde | 16.05.2010 | Tacuary | - | Club Nacional | 0:3 | ||||
| 21. Ronde | 22.05.2010 | 3 de Febrero | - | Tacuary | 1:0 | ||||
| 22. Ronde | 28.05.2010 | Tacuary | - | Sport Colombia | 2:2 | |
Paraguay