| 1. Ronde | 16.01.2021 | Real Cartagena | - | Cortuluá | 2:1 | ||||
| 3. Ronde | 01.02.2021 | Real Cartagena | - | Barranquilla FC | 1:0 | ||||
| 4. Ronde | 09.02.2021 | Valledupar FC | - | Real Cartagena | 2:0 | ||||
| 5. Ronde | 11.02.2021 | Real Cartagena | - | Llaneros FC | 3:1 | ||||
| 6. Ronde | 16.02.2021 | Unión Magdalena | - | Real Cartagena | 2:1 | ||||
| 10. Ronde | 06.03.2021 | Tigres FC | - | Real Cartagena | 0:0 | ||||
| 11. Ronde | 14.03.2021 | Real Santander | - | Real Cartagena | 0:3 | ||||
| 13. Ronde | 28.03.2021 | Fortaleza FC | - | Real Cartagena | 1:1 | ||||
| 14. Ronde | 03.04.2021 | Real Cartagena | - | Leones FC | 2:1 |  |
|||
| 15. Ronde | 09.04.2021 | Atlético Huila | - | Real Cartagena | 4:1 |
Colombia