| 1. Ronde | 13.08.2022 | Sampdoria | - | Atalanta | 0:2 | ||||
| 2. Ronde | 22.08.2022 | Sampdoria | - | Juventus | 0:0 | ||||
| 3. Ronde | 28.08.2022 | US Salernitana 1919 | - | Sampdoria | 4:0 | ||||
| 4. Ronde | 31.08.2022 | Sampdoria | - | Lazio | 1:1 | ||||
| 5. Ronde | 04.09.2022 | Hellas Verona | - | Sampdoria | 2:1 |  |
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| 7. Ronde | 17.09.2022 | Spezia Calcio | - | Sampdoria | 2:1 | ||||
| 8. Ronde | 02.10.2022 | Sampdoria | - | AC Monza | 0:3 | ||||
| 9. Ronde | 08.10.2022 | Bologna FC | - | Sampdoria | 1:1 | ||||
| 10. Ronde | 17.10.2022 | Sampdoria | - | AS Roma | 0:1 | |
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| 11. Ronde | 24.10.2022 | US Cremonese | - | Sampdoria | 0:1 |  |
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| 12. Ronde | 29.10.2022 | Inter | - | Sampdoria | 3:0 | |
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| 13. Ronde | 06.11.2022 | Sampdoria | - | ACF Fiorentina | 0:2 | ||||
| 14. Ronde | 09.11.2022 | Torino FC | - | Sampdoria | 2:0 | |
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| 18. Ronde | 16.01.2023 | Empoli FC | - | Sampdoria | 1:0 | ||||
| 19. Ronde | 22.01.2023 | Sampdoria | - | Udinese Calcio | 0:1 | ||||
| 21. Ronde | 06.02.2023 | AC Monza | - | Sampdoria | 2:2 |
Gambia