| 1. Ronde | 07.02.2016 | Danubio | - | Juventud de Las Piedras | 2:1 | ||||
| 2. Ronde | 14.02.2016 | CA Cerro | - | Danubio | 1:0 |  |
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| 3. Ronde | 21.02.2016 | Danubio | - | El Tanque Sisley | 3:3 | |
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| 4. Ronde | 28.02.2016 | Defensor Sporting | - | Danubio | 3:2 | |
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| 11. Ronde | 08.05.2016 | Liverpool | - | Danubio | 0:3 | |
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| 12. Ronde | 14.05.2016 | Danubio | - | Villa Teresa | 1:1 | ||||
| 14. Ronde | 28.05.2016 | Danubio | - | Montevideo Wanderers | 1:4 |
Uruguay