| 1. Ronde | 22.07.2018 | Atenas | - | Defensor Sporting | 2:5 |  |
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| 2. Ronde | 28.07.2018 | Defensor Sporting | - | Danubio | 1:2 | |
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| 3. Ronde | 05.08.2018 | Torque | - | Defensor Sporting | 0:0 | ||||
| 4. Ronde | 12.08.2018 | Defensor Sporting | - | Rampla Juniors | 2:2 | |
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| 5. Ronde | 19.08.2018 | Fénix | - | Defensor Sporting | 1:2 | ||||
| 7. Ronde | 02.09.2018 | Progreso | - | Defensor Sporting | 0:0 | ||||
| 9. Ronde | 16.09.2018 | Defensor Sporting | - | Racing | 2:1 | ||||
| 10. Ronde | 23.09.2018 | River Plate | - | Defensor Sporting | 3:2 | ||||
| 14. Ronde | 28.10.2018 | Boston River | - | Defensor Sporting | 3:1 |
Uruguay