| 11. Ronde | 20.02.2021 | FC Sheriff | - | FC Sfîntul Gheorghe | 4:1 | ||||
| 23. Ronde | 01.03.2021 | FC Milsami | - | FC Sheriff | 0:1 | ||||
| 24. Ronde | 06.03.2021 | FC Sheriff | - | Dinamo-Auto | 7:0 | ||||
| 25. Ronde | 13.03.2021 | FC Floreşti | - | FC Sheriff | 0:6 |  |
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| 26. Ronde | 19.03.2021 | FC Sheriff | - | CS Petrocub | 0:0 | ||||
| 28. Ronde | 16.04.2021 | Speranţa Nisporeni | - | FC Sheriff | 0:10 | |
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| 29. Ronde | 24.04.2021 | FC Sheriff | - | FC Sfîntul Gheorghe | 2:0 | ||||
| 30. Ronde | 29.04.2021 | FC Codru Lozova | - | FC Sheriff | 0:6 | |
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| 31. Ronde | 08.05.2021 | FC Zimbru | - | FC Sheriff | 0:1 | ||||
| 32. Ronde | 12.05.2021 | FC Sheriff | - | FC Milsami | 6:0 |  |
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| 33. Ronde | 15.05.2021 | Dinamo-Auto | - | FC Sheriff | 0:7 | ||||
| 34. Ronde | 19.05.2021 | FC Sheriff | - | FC Floreşti | 3:0 | ||||
| 35. Ronde | 22.05.2021 | CS Petrocub | - | FC Sheriff | 0:1 | ||||
| 36. Ronde | 26.05.2021 | FC Sheriff | - | Dacia Buiucani | 1:1 |
Malawi