| 4. Ronde | 28.08.2021 | FC Wiltz 71 | - | RFCU Luxemburg | 2:3 | ||||
| 5. Ronde | 12.09.2021 | RFCU Luxemburg | - | F91 Dudelange | 3:4 |  |
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| 9. Ronde | 17.10.2021 | Union Titus Pétange | - | RFCU Luxemburg | 4:2 | ||||
| 18. Ronde | 20.02.2022 | RFCU Luxemburg | - | FC Wiltz 71 | 1:3 | |
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| 19. Ronde | 26.02.2022 | F91 Dudelange | - | RFCU Luxemburg | 1:1 | ||||
| 20. Ronde | 06.03.2022 | RFCU Luxemburg | - | Jeunesse Esch | 0:0 | ||||
| 24. Ronde | 10.04.2022 | US Mondorf | - | RFCU Luxemburg | 2:3 | ||||
| 25. Ronde | 16.04.2022 | RFCU Luxemburg | - | Etzella Ettelbruck | 1:2 | |
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| 26. Ronde | 24.04.2022 | FC Differdange 03 | - | RFCU Luxemburg | 4:0 | ||||
| 28. Ronde | 07.05.2022 | CS FOLA Esch | - | RFCU Luxemburg | 2:0 | ||||
| 29. Ronde | 15.05.2022 | RFCU Luxemburg | - | UNA Strassen | 6:1 |  |
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| 30. Ronde | 22.05.2022 | Swift Hesperange | - | RFCU Luxemburg | 2:0 |
Luxemburg