| 4. Ronde | 11.08.2021 | CS Cartaginés | - | AD San Carlos | 5:1 | ||||
| 5. Ronde | 14.08.2021 | AD San Carlos | - | Jicaral | 0:0 | ||||
| 7. Ronde | 25.08.2021 | Sporting FC | - | AD San Carlos | 0:0 | ||||
| 8. Ronde | 30.08.2021 | AD San Carlos | - | AD Guanacasteca | 0:1 | ||||
| 10. Ronde | 13.09.2021 | AD San Carlos | - | Deportivo Saprissa | 1:0 | ||||
| 11. Ronde | 15.09.2021 | Municipal Grecia | - | AD San Carlos | 3:2 | ||||
| 13. Ronde | 26.09.2021 | AD San Carlos | - | Guadalupe | 4:2 | ||||
| 15. Ronde | 13.10.2021 | AD San Carlos | - | CS Cartaginés | 0:1 | ||||
| 16. Ronde | 17.10.2021 | Jicaral | - | AD San Carlos | 0:4 | ||||
| 17. Ronde | 23.10.2021 | AD San Carlos | - | CS Herediano | 0:0 | ||||
| 20. Ronde | 21.11.2021 | AD San Carlos | - | Santos de Guápiles | 2:4 | ||||
| 21. Ronde | 24.11.2021 | Deportivo Saprissa | - | AD San Carlos | 3:0 | ||||
| 22. Ronde | 28.11.2021 | AD San Carlos | - | Municipal Grecia | 1:3 |
Costa Rica
Nicaragua