| 19. Ronde | 02.07.2021 | Shamrock Rovers | - | Dundalk FC | 3:1 | ||||
| 21. Ronde | 16.07.2021 | Derry City | - | Shamrock Rovers | 2:4 |  |
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| 22. Ronde | 30.07.2021 | Shamrock Rovers | - | St Patrick's Athletic | 3:1 | ||||
| 23. Ronde | 08.08.2021 | Shamrock Rovers | - | Longford Town | 1:0 | ||||
| 24. Ronde | 15.08.2021 | Drogheda United | - | Shamrock Rovers | 0:1 | ||||
| 26. Ronde | 03.09.2021 | Finn Harps | - | Shamrock Rovers | 2:1 | ||||
| 27. Ronde | 10.09.2021 | Shamrock Rovers | - | Waterford FC | 2:0 | ||||
| 20. Ronde | 18.09.2021 | Sligo Rovers | - | Shamrock Rovers | 0:1 |  |
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| 28. Ronde | 24.09.2021 | St Patrick's Athletic | - | Shamrock Rovers | 0:1 | ||||
| 29. Ronde | 01.10.2021 | Shamrock Rovers | - | Derry City | 2:1 | ||||
| 30. Ronde | 08.10.2021 | Dundalk FC | - | Shamrock Rovers | 1:0 | ||||
| 31. Ronde | 15.10.2021 | Shamrock Rovers | - | Sligo Rovers | 2:0 | ||||
| 25. Ronde | 18.10.2021 | Shamrock Rovers | - | Bohemian FC | 1:1 | |
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| 32. Ronde | 23.10.2021 | Longford Town | - | Shamrock Rovers | 0:1 | ||||
| 33. Ronde | 29.10.2021 | Shamrock Rovers | - | Finn Harps | 3:0 | ||||
| 35. Ronde | 12.11.2021 | Bohemian FC | - | Shamrock Rovers | 3:1 | ||||
| 36. Ronde | 19.11.2021 | Shamrock Rovers | - | Drogheda United | 2:1 |
Ierland