| 14. Ronde | 29.01.2022 | Lazio Roma [A-jun] | - | AC Perugia Calcio [A-jun] | 4:0 | ||||
| 15. Ronde | 05.02.2022 | FC Crotone [A-jun] | - | Lazio Roma [A-jun] | 0:7 | ||||
| 17. Ronde | 19.02.2022 | Ternana Calcio [A-jun] | - | Lazio Roma [A-jun] | 2:3 | ||||
| 18. Ronde | 26.02.2022 | Lazio Roma [A-jun] | - | Reggina 1914 [A-jun] | 0:1 | ||||
| 19. Ronde | 05.03.2022 | Cesena FC [A-jun] | - | Lazio Roma [A-jun] | 3:1 | ||||
| 20. Ronde | 12.03.2022 | Lazio Roma [A-jun] | - | Ascoli Calcio [A-jun] | 1:1 | ||||
| 21. Ronde | 19.03.2022 | Spezia Calcio [A-jun] | - | Lazio Roma [A-jun] | 4:1 | ||||
| 25. Ronde | 16.04.2022 | Pisa SC [A-jun] | - | Lazio Roma [A-jun] | 2:1 |
Estland