| 2. Ronde | 15.01.2023 | Deportivo Toluca | - | CF América | 2:2 | ||||
| 3. Ronde | 22.01.2023 | CF América | - | Puebla FC | 2:2 | ||||
| 5. Ronde | 05.02.2023 | Santos Laguna | - | CF América | 2:2 |  |
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| 6. Ronde | 12.02.2023 | CF América | - | Club Necaxa | 2:1 | ||||
| 7. Ronde | 15.02.2023 | Atlético San Luis | - | CF América | 1:3 | ||||
| 8. Ronde | 20.02.2023 | CF América | - | Club Tijuana | 2:1 | ||||
| 10. Ronde | 05.03.2023 | CF América | - | CF Pachuca | 0:3 | ||||
| 11. Ronde | 12.03.2023 | UANL Tigres | - | CF América | 0:2 | ||||
| 16. Ronde | 23.04.2023 | CF América | - | Pumas UNAM | 1:1 | ||||
| 17. Ronde | 29.04.2023 | FC Juárez | - | CF América | 0:1 |
Colombia