| 8. Ronde | 11.09.2021 | Jocoro FC | - | AD Chalatenango | 3:1 | ||||
| 9. Ronde | 15.09.2021 | Jocoro FC | - | Municipal Limeño | 3:1 | ||||
| 10. Ronde | 19.09.2021 | Platense Zacatecoluca | - | Jocoro FC | 1:1 |  |
|||
| 11. Ronde | 25.09.2021 | Jocoro FC | - | Alianza | 3:3 | ||||
| 12. Ronde | 02.10.2021 | Jocoro FC | - | Luis Ángel Firpo | 2:1 | ||||
| 13. Ronde | 17.10.2021 | Once Municipal | - | Jocoro FC | 2:2 | ||||
| 14. Ronde | 20.10.2021 | Jocoro FC | - | FAS | 0:0 | ||||
| 15. Ronde | 24.10.2021 | Isidro Metapán | - | Jocoro FC | 1:1 | ||||
| 16. Ronde | 30.10.2021 | Jocoro FC | - | Atlético Marte | 1:1 | ||||
| 17. Ronde | 03.11.2021 | Santa Tecla FC | - | Jocoro FC | 2:1 | ||||
| 18. Ronde | 06.11.2021 | Jocoro FC | - | CD Águila | 2:2 | ||||
| 19. Ronde | 14.11.2021 | AD Chalatenango | - | Jocoro FC | 2:0 |  |
|||
| 21. Ronde | 21.11.2021 | Jocoro FC | - | Platense Zacatecoluca | 1:1 | ||||
| 22. Ronde | 27.11.2021 | Alianza | - | Jocoro FC | 2:0 |
El Salvador