| 1. Ronde | 01.08.2021 | Once Municipal | - | CD Águila | 2:2 | ||||
| 2. Ronde | 08.08.2021 | CD Águila | - | FAS | 1:1 |  |
|||
| 3. Ronde | 12.08.2021 | Isidro Metapán | - | CD Águila | 2:2 | ||||
| 4. Ronde | 15.08.2021 | CD Águila | - | Atlético Marte | 4:1 | |
|||
| 8. Ronde | 12.09.2021 | Municipal Limeño | - | CD Águila | 1:0 | ||||
| 22. Ronde | 27.11.2021 | Luis Ángel Firpo | - | CD Águila | 1:0 |
El Salvador