| 1. Ronde | 11.09.2021 | Panetolikos | - | Asteras Tripolis | 0:0 | ||||
| 2. Ronde | 19.09.2021 | Asteras Tripolis | - | PAOK Saloniki | 0:1 | ||||
| 3. Ronde | 22.09.2021 | OFI Heraklion | - | Asteras Tripolis | 0:0 |  |
|||
| 8. Ronde | 31.10.2021 | PAS Giannina | - | Asteras Tripolis | 1:1 | |
|||
| 9. Ronde | 07.11.2021 | Asteras Tripolis | - | Lamia | 0:1 | ||||
| 10. Ronde | 20.11.2021 | Ionikos Nikea | - | Asteras Tripolis | 1:1 | ||||
| 12. Ronde | 05.12.2021 | Aris Saloniki | - | Asteras Tripolis | 1:0 | ||||
| 13. Ronde | 11.12.2021 | Asteras Tripolis | - | AEK Athene | 0:0 | |
|||
| 15. Ronde | 19.12.2021 | PAOK Saloniki | - | Asteras Tripolis | 3:2 | |
|||
| 22. Ronde | 23.02.2022 | Lamia | - | Asteras Tripolis | 0:2 | ||||
| 26. Ronde | 06.03.2022 | AEK Athene | - | Asteras Tripolis | 2:1 |
Spanje