| 1. Ronde | 06.01.2013 | Club San Luis | - | Santos Laguna | 1:1 |  |
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| 2. Ronde | 13.01.2013 | Cruz Azul | - | Club San Luis | 2:1 |  |
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| 3. Ronde | 20.01.2013 | Club San Luis | - | Monarcas Morelia | 1:2 | ||||
| 4. Ronde | 27.01.2013 | CF Monterrey | - | Club San Luis | 3:2 | |
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| 5. Ronde | 03.02.2013 | Deportivo Guadalajara | - | Club San Luis | 1:1 | ||||
| 6. Ronde | 10.02.2013 | Club San Luis | - | Puebla FC | 1:3 | ||||
| 8. Ronde | 24.02.2013 | Club San Luis | - | Pumas UNAM | 0:2 | ||||
| 9. Ronde | 03.03.2013 | CF Pachuca | - | Club San Luis | 2:1 | ||||
| 10. Ronde | 10.03.2013 | Club San Luis | - | UANL Tigres | 1:2 | ||||
| 11. Ronde | 17.03.2013 | CF América | - | Club San Luis | 1:1 |
Colombia