| 2. Ronde | 29.08.2021 | US Colomiers [A-jun] | - | Toulouse FC [A-jun] | 1:1 | ||||
| 3. Ronde | 05.09.2021 | FC Istres [A-jun] | - | US Colomiers [A-jun] | 1:1 | ||||
| 4. Ronde | 12.09.2021 | US Colomiers [A-jun] | - | Pieve di Lota [A-jun] | 7:2 | ||||
| 6. Ronde | 26.09.2021 | AS Saint-Étienne [A-jun] | - | US Colomiers [A-jun] | 2:1 | ||||
| 7. Ronde | 03.10.2021 | US Colomiers [A-jun] | - | AC Ajaccio [A-jun] | 3:1 | ||||
| 8. Ronde | 10.10.2021 | Nîmes Olympique [A-jun] | - | US Colomiers [A-jun] | 1:0 | ||||
| 16. Ronde | 23.01.2022 | Pieve di Lota [A-jun] | - | US Colomiers [A-jun] | 0:3 | ||||
| 17. Ronde | 06.02.2022 | US Colomiers [A-jun] | - | AS Monaco [A-jun] | 1:1 | ||||
| 19. Ronde | 06.03.2022 | AC Ajaccio [A-jun] | - | US Colomiers [A-jun] | 3:0 | ||||
| 20. Ronde | 20.03.2022 | US Colomiers [A-jun] | - | Nîmes Olympique [A-jun] | 2:0 | ||||
| 26. Ronde | 15.05.2022 | US Colomiers [A-jun] | - | OGC Nice [A-jun] | 2:1 |
Frankrijk