| 1. Ronde | 16.04.2022 | Manta FC [U19] | - | Atlético Santo Domingo [U19] | 0:1 | ||||
| 3. Ronde | 07.05.2022 | Atlético Santo Domingo [U19] | - | Delfín SC [U19] | 0:0 | ||||
| 4. Ronde | 14.05.2022 | Emelec [U19] | - | Atlético Santo Domingo [U19] | 3:0 |  |
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| 5. Ronde | 28.05.2022 | Atlético Santo Domingo [U19] | - | Guayaquil City [U19] | 0:1 | ||||
| 8. Ronde | 15.07.2022 | Delfín SC [U19] | - | Atlético Santo Domingo [U19] | 1:0 | ||||
| 9. Ronde | 30.07.2022 | Atlético Santo Domingo [U19] | - | Emelec [U19] | 1:2 | ||||
| 10. Ronde | 05.08.2022 | Guayaquil City [U19] | - | Atlético Santo Domingo [U19] | 0:1 |
Ecuador