| 1. Ronde | 10.08.2024 | NEC Nijmegen | - | FC Twente | 1:2 | ||||
| 2. Ronde | 17.08.2024 | FC Twente | - | Sparta Rotterdam | 1:1 |  |
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| 4. Ronde | 01.09.2024 | FC Utrecht | - | FC Twente | 2:1 | ||||
| 5. Ronde | 14.09.2024 | FC Twente | - | PEC Zwolle | 1:1 | |
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| 3. Ronde | 17.09.2024 | FC Twente | - | sc Heerenveen | 2:0 | |
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| 6. Ronde | 22.09.2024 | Almere City FC | - | FC Twente | 0:5 | |
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| 7. Ronde | 29.09.2024 | FC Twente | - | NAC Breda | 1:0 | ||||
| 8. Ronde | 06.10.2024 | Feyenoord | - | FC Twente | 2:1 | |
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| 9. Ronde | 19.10.2024 | RKC Waalwijk | - | FC Twente | 2:2 | |
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| 10. Ronde | 27.10.2024 | FC Twente | - | Heracles Almelo | 5:0 | ||||
| 12. Ronde | 10.11.2024 | FC Twente | - | AFC Ajax | 2:2 | ||||
| 13. Ronde | 23.11.2024 | Fortuna Sittard | - | FC Twente | 1:2 | |
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| 14. Ronde | 01.12.2024 | FC Twente | - | Go Ahead Eagles | 3:2 | |
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| 15. Ronde | 06.12.2024 | PSV | - | FC Twente | 6:1 | |
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| 16. Ronde | 15.12.2024 | FC Twente | - | FC Groningen | 2:0 | |
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| 17. Ronde | 21.12.2024 | AZ Alkmaar | - | FC Twente | 1:0 | ||||
| 18. Ronde | 12.01.2025 | FC Twente | - | Willem II | 6:2 | |
Nederland