| 1. Ronde | 15.08.2022 | FC Cartagena | - | SD Ponferradina | 2:3 |  |
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| 2. Ronde | 21.08.2022 | SD Huesca | - | FC Cartagena | 2:3 | |
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| 3. Ronde | 26.08.2022 | FC Cartagena | - | Real Zaragoza | 1:0 | ||||
| 11. Ronde | 16.10.2022 | FC Cartagena | - | UD Ibiza | 2:0 | ||||
| 13. Ronde | 30.10.2022 | FC Cartagena | - | Granada CF | 0:0 | ||||
| 14. Ronde | 03.11.2022 | FC Cartagena | - | Málaga CF | 2:1 | |
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| 16. Ronde | 21.11.2022 | CD Mirandés | - | FC Cartagena | 2:1 | ||||
| 17. Ronde | 27.11.2022 | FC Cartagena | - | SD Eibar | 2:1 | ||||
| 18. Ronde | 04.12.2022 | FC Andorra | - | FC Cartagena | 0:1 | ||||
| 19. Ronde | 07.12.2022 | FC Cartagena | - | Villarreal CF B | 0:1 | ||||
| 20. Ronde | 11.12.2022 | Sporting Gijón | - | FC Cartagena | 0:0 | ||||
| 21. Ronde | 17.12.2022 | FC Cartagena | - | Racing Santander | 0:3 |
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