| 8. Ronde | 06.11.2021 | Pisa SC [A-jun] | - | Reggina 1914 [A-jun] | 0:0 | ||||
| 9. Ronde | 20.11.2021 | Ascoli Calcio [A-jun] | - | Pisa SC [A-jun] | 3:0 | ||||
| 12. Ronde | 11.12.2021 | Lazio Roma [A-jun] | - | Pisa SC [A-jun] | 3:0 |  |
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| 16. Ronde | 12.02.2022 | Pisa SC [A-jun] | - | Cosenza Calcio [A-jun] | 3:1 | |
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| 18. Ronde | 26.02.2022 | Pisa SC [A-jun] | - | Cesena FC [A-jun] | 1:3 |  |
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| 19. Ronde | 05.03.2022 | US Salernitana 1919 [A-jun] | - | Pisa SC [A-jun] | 2:1 | |
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| 22. Ronde | 26.03.2022 | Pisa SC [A-jun] | - | Ascoli Calcio [A-jun] | 1:0 | ||||
| 23. Ronde | 02.04.2022 | FC Crotone [A-jun] | - | Pisa SC [A-jun] | 1:0 | ||||
| 24. Ronde | 09.04.2022 | AC Perugia Calcio [A-jun] | - | Pisa SC [A-jun] | 1:2 | ||||
| 25. Ronde | 16.04.2022 | Pisa SC [A-jun] | - | Lazio Roma [A-jun] | 2:1 | |
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| 26. Ronde | 23.04.2022 | Benevento Calcio [A-jun] | - | Pisa SC [A-jun] | 1:2 |
Frankrijk