| 1. Ronde | 12.02.2022 | Vitória Guimarães [A-jun] | - | FC Alverca [A-jun] | 2:2 | ||||
| 2. Ronde | 19.02.2022 | Sporting Braga [A-jun] | - | Vitória Guimarães [A-jun] | 3:0 | ||||
| 3. Ronde | 26.02.2022 | Vitória Guimarães [A-jun] | - | FC Porto [A-jun] | 1:2 | ||||
| 4. Ronde | 06.03.2022 | SL Benfica [A-jun] | - | Vitória Guimarães [A-jun] | 4:1 | ||||
| 6. Ronde | 02.04.2022 | Vitória Guimarães [A-jun] | - | GD Estoril [A-jun] | 4:0 | ||||
| 7. Ronde | 09.04.2022 | Rio Ave FC [A-jun] | - | Vitória Guimarães [A-jun] | 3:3 | ||||
| 9. Ronde | 23.04.2022 | Vitória Guimarães [A-jun] | - | Sporting Braga [A-jun] | 0:1 |
Estland