| 1. Ronde | 16.04.2022 | Manta FC [U19] | - | Atlético Santo Domingo [U19] | 0:1 |  |
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| 2. Ronde | 23.04.2022 | 9 de Octubre [U19] | - | Atlético Santo Domingo [U19] | 4:2 |  |
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| 3. Ronde | 07.05.2022 | Atlético Santo Domingo [U19] | - | Delfín SC [U19] | 0:0 | ||||
| 4. Ronde | 14.05.2022 | Emelec [U19] | - | Atlético Santo Domingo [U19] | 3:0 | ||||
| 6. Ronde | 04.06.2022 | Atlético Santo Domingo [U19] | - | Manta FC [U19] | 3:1 | |
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| 7. Ronde | 10.07.2022 | Atlético Santo Domingo [U19] | - | 9 de Octubre [U19] | 3:0 | ||||
| 8. Ronde | 15.07.2022 | Delfín SC [U19] | - | Atlético Santo Domingo [U19] | 1:0 | |
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| 9. Ronde | 30.07.2022 | Atlético Santo Domingo [U19] | - | Emelec [U19] | 1:2 | |
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| 10. Ronde | 05.08.2022 | Guayaquil City [U19] | - | Atlético Santo Domingo [U19] | 0:1 |
Ecuador