| 1. Ronde | 19.09.2021 | SS San Giovanni | - | AC Juvenes/Dogana | 4:0 | ||||
| 4. Ronde | 16.10.2021 | SS Pennarossa | - | AC Juvenes/Dogana | 0:0 | ||||
| 5. Ronde | 19.10.2021 | AC Juvenes/Dogana | - | FC Domagnano | 2:1 | ||||
| 6. Ronde | 23.10.2021 | AC Juvenes/Dogana | - | FC Fiorentino | 0:1 | ||||
| 7. Ronde | 31.10.2021 | SP La Fiorita | - | AC Juvenes/Dogana | 2:2 | ||||
| 9. Ronde | 21.11.2021 | SC Faetano | - | AC Juvenes/Dogana | 3:1 | ||||
| 10. Ronde | 28.11.2021 | AC Juvenes/Dogana | - | SS Virtus | 1:2 | ||||
| 12. Ronde | 11.12.2021 | AC Juvenes/Dogana | - | AC Libertas | 1:7 | ||||
| 13. Ronde | 18.12.2021 | SS Cosmos | - | AC Juvenes/Dogana | 1:1 | ||||
| 18. Ronde | 29.01.2022 | AC Juvenes/Dogana | - | SS Folgore/Falciano | 0:4 | ||||
| 22. Ronde | 19.02.2022 | AC Juvenes/Dogana | - | SP La Fiorita | 0:4 | ||||
| 14. Ronde | 22.02.2022 | AC Juvenes/Dogana | - | SP Cailungo | 0:4 | ||||
| 23. Ronde | 27.02.2022 | SS Murata | - | AC Juvenes/Dogana | 0:1 | ||||
| 16. Ronde | 03.04.2022 | AC Juvenes/Dogana | - | SS San Giovanni | 4:1 | ||||
| 17. Ronde | 06.04.2022 | SP Tre Penne | - | AC Juvenes/Dogana | 7:1 | ||||
| 28. Ronde | 09.04.2022 | AC Juvenes/Dogana | - | SS Cosmos | 3:1 |  |
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| 29. Ronde | 13.04.2022 | SP Cailungo | - | AC Juvenes/Dogana | 2:2 |
San Marino