| 1. Ronde | 07.08.2022 | FC Differdange 03 | - | RFCU Luxemburg | 2:3 |  |
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| 2. Ronde | 14.08.2022 | UNA Strassen | - | FC Differdange 03 | 3:2 | ||||
| 3. Ronde | 21.08.2022 | FC Differdange 03 | - | Union Titus Pétange | 1:1 | |
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| 4. Ronde | 28.08.2022 | Etzella Ettelbruck | - | FC Differdange 03 | 0:2 | ||||
| 5. Ronde | 04.09.2022 | FC Differdange 03 | - | CS FOLA Esch | 6:0 | |
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| 6. Ronde | 11.09.2022 | FC Mondercange | - | FC Differdange 03 | 0:0 |  |
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| 7. Ronde | 18.09.2022 | US Mondorf | - | FC Differdange 03 | 0:1 | ||||
| 9. Ronde | 16.10.2022 | F91 Dudelange | - | FC Differdange 03 | 3:1 | ||||
| 10. Ronde | 23.10.2022 | FC Differdange 03 | - | UN Käerjéng | 2:2 | ||||
| 11. Ronde | 06.11.2022 | Victoria Rosport | - | FC Differdange 03 | 2:3 | |
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| 12. Ronde | 13.11.2022 | FC Differdange 03 | - | FC Wiltz 71 | 2:1 | ||||
| 13. Ronde | 26.11.2022 | Jeunesse Esch | - | FC Differdange 03 | 1:0 | ||||
| 14. Ronde | 04.12.2022 | FC Differdange 03 | - | Progrès Niedercorn | 2:3 | |
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| 15. Ronde | 10.12.2022 | US Hostert | - | FC Differdange 03 | 0:5 | |
Portugal
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