| 2. Ronde | 10.04.2022 | Santos FC | - | Deportivo Coopsol | 2:2 | ||||
| 3. Ronde | 17.04.2022 | Unión Huaral | - | Santos FC | 0:0 | ||||
| 4. Ronde | 24.04.2022 | Santos FC | - | Juan Aurich | 4:0 | ||||
| 5. Ronde | 01.05.2022 | Alianza Universidad | - | Santos FC | 4:1 | ||||
| 6. Ronde | 08.05.2022 | Santos FC | - | Comerciantes Unidos | 2:0 | ||||
| 7. Ronde | 15.05.2022 | Unión Comercio | - | Santos FC | 3:1 | ||||
| 13. Ronde | 26.06.2022 | Los Chankas | - | Santos FC | 2:0 |
Peru