| 1. Ronde | 02.07.2021 | FC Zimbru | - | Dinamo-Auto | 3:0 | ||||
| 2. Ronde | 17.07.2021 | FC Zimbru | - | FC Floreşti | 4:0 | ||||
| 4. Ronde | 01.08.2021 | FC Zimbru | - | FC Milsami | 0:2 | ||||
| 6. Ronde | 14.08.2021 | FC Zimbru | - | FC Bălţi | 2:3 | ||||
| 9. Ronde | 11.09.2021 | FC Floreşti | - | FC Zimbru | 1:3 | ||||
| 10. Ronde | 19.09.2021 | FC Zimbru | - | FC Sheriff | 1:1 | ||||
| 13. Ronde | 02.10.2021 | FC Bălţi | - | FC Zimbru | 2:1 | ||||
| 14. Ronde | 17.10.2021 | FC Zimbru | - | CS Petrocub | 0:1 | ||||
| 15. Ronde | 22.10.2021 | FC Zimbru | - | Dinamo-Auto | 1:2 | ||||
| 16. Ronde | 30.10.2021 | FC Zimbru | - | FC Floreşti | 3:0 | ||||
| 18. Ronde | 20.11.2021 | FC Zimbru | - | FC Milsami | 1:2 | ||||
| 19. Ronde | 27.11.2021 | FC Sfîntul Gheorghe | - | FC Zimbru | 1:1 | ||||
| 3. Ronde | 11.12.2021 | FC Sheriff | - | FC Zimbru | 4:0 | ||||
| 20. Ronde | 12.03.2022 | FC Zimbru | - | FC Bălţi | 2:1 | ||||
| 22. Ronde | 03.04.2022 | Dinamo-Auto | - | FC Zimbru | 0:0 |  |
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| 24. Ronde | 16.04.2022 | FC Zimbru | - | FC Sheriff | 1:1 | ||||
| 25. Ronde | 21.04.2022 | FC Milsami | - | FC Zimbru | 3:0 | ||||
| 26. Ronde | 30.04.2022 | FC Zimbru | - | FC Sfîntul Gheorghe | 1:0 | ||||
| 27. Ronde | 08.05.2022 | FC Bălţi | - | FC Zimbru | 1:0 | ||||
| 28. Ronde | 14.05.2022 | FC Zimbru | - | CS Petrocub | 0:3 |
Moldavië