| 1. Ronde | 07.08.2021 | Stade Plabennec | - | SM Caen B | 0:1 | ||||
| 2. Ronde | 14.08.2021 | SM Caen B | - | Vannes OC | 0:0 | ||||
| 3. Ronde | 21.08.2021 | St-Pryvé St-Hilaire | - | SM Caen B | 2:0 | ||||
| 5. Ronde | 04.09.2021 | Blois Foot 41 | - | SM Caen B | 2:1 |  |
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| 6. Ronde | 11.09.2021 | SM Caen B | - | SO Romorantin | 0:0 | ||||
| 7. Ronde | 18.09.2021 | FC Lorient B | - | SM Caen B | 0:1 | ||||
| 9. Ronde | 09.10.2021 | EA Guingamp B | - | SM Caen B | 1:1 | ||||
| 11. Ronde | 06.11.2021 | AS Poissy | - | SM Caen B | 1:0 | |
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| 12. Ronde | 20.11.2021 | SM Caen B | - | FC Versailles | 1:0 | ||||
| 13. Ronde | 04.12.2021 | C'Chartres Football | - | SM Caen B | 4:0 | ||||
| 14. Ronde | 11.12.2021 | SM Caen B | - | US Saint-Malo | 0:0 | |
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| 16. Ronde | 22.01.2022 | Vannes OC | - | SM Caen B | 1:4 | ||||
| 20. Ronde | 05.03.2022 | SO Romorantin | - | SM Caen B | 0:1 |
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