| 1. Ronde | 22.08.2021 | SC Toulon [A-jun] | - | Montpellier HSC [A-jun] | 2:1 |  |
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| 2. Ronde | 29.08.2021 | Montpellier HSC [A-jun] | - | Olympique Marseille [A-jun] | 2:1 | |
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| 3. Ronde | 05.09.2021 | AS Cannes [A-jun] | - | Montpellier HSC [A-jun] | 1:1 | |
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| 7. Ronde | 03.10.2021 | Pieve di Lota [A-jun] | - | Montpellier HSC [A-jun] | 0:2 | |
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| 9. Ronde | 17.10.2021 | US Colomiers [A-jun] | - | Montpellier HSC [A-jun] | 1:0 | ||||
| 10. Ronde | 24.10.2021 | Montpellier HSC [A-jun] | - | AC Ajaccio [A-jun] | 2:2 | |
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| 11. Ronde | 14.11.2021 | Nîmes Olympique [A-jun] | - | Montpellier HSC [A-jun] | 1:3 | |
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| 12. Ronde | 21.11.2021 | AS Saint-Étienne [A-jun] | - | Montpellier HSC [A-jun] | 0:0 | ||||
| 13. Ronde | 27.11.2021 | Montpellier HSC [A-jun] | - | AS Béziers [A-jun] | 1:0 | ||||
| 16. Ronde | 22.01.2022 | OGC Nice [A-jun] | - | Montpellier HSC [A-jun] | 1:2 | ||||
| 17. Ronde | 06.02.2022 | Montpellier HSC [A-jun] | - | Toulouse FC [A-jun] | 2:1 |
Frankrijk
Marokko