| 1. Ronde | 07.08.2021 | RC Lens B | - | FC Fleury 91 | 1:3 | ||||
| 2. Ronde | 14.08.2021 | US Lusitanos | - | RC Lens B | 2:0 | ||||
| 3. Ronde | 21.08.2021 | RC Lens B | - | FC Metz B | 0:2 | ||||
| 4. Ronde | 28.08.2021 | SC Schiltigheim | - | RC Lens B | 1:0 | ||||
| 7. Ronde | 18.09.2021 | RC Lens B | - | ASM Belfort | 1:1 | ||||
| 8. Ronde | 25.09.2021 | Sainte-Geneviève-des-Bois | - | RC Lens B | 1:1 | ||||
| 9. Ronde | 09.10.2021 | RC Lens B | - | Stade de Reims B | 2:5 | ||||
| 10. Ronde | 23.10.2021 | AJ Auxerre B | - | RC Lens B | 1:1 |  |
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| 11. Ronde | 06.11.2021 | RC Lens B | - | FCSR Haguenau | 3:2 | ||||
| 15. Ronde | 15.01.2022 | AS Beauvais | - | RC Lens B | 2:1 | ||||
| 16. Ronde | 22.01.2022 | RC Lens B | - | US Lusitanos | 0:1 | ||||
| 17. Ronde | 05.02.2022 | FC Metz B | - | RC Lens B | 0:0 | ||||
| 19. Ronde | 19.02.2022 | Entente SSG | - | RC Lens B | 1:0 | ||||
| 18. Ronde | 26.02.2022 | RC Lens B | - | SC Schiltigheim | 1:1 | ||||
| 20. Ronde | 05.03.2022 | RC Lens B | - | SAS Épinal | 0:1 | ||||
| 22. Ronde | 19.03.2022 | RC Lens B | - | Sainte-Geneviève-des-Bois | 0:0 | ||||
| 25. Ronde | 16.04.2022 | FCSR Haguenau | - | RC Lens B | 0:1 | ||||
| 26. Ronde | 23.04.2022 | RC Lens B | - | Paris 13 Atletico | 1:1 | ||||
| 27. Ronde | 30.04.2022 | FC 93 Bobigny | - | RC Lens B | 3:2 |
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