| 7. Ronde | 28.08.2021 | HNK Šibenik | - | NK Istra 1961 | 3:1 |  |
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| 12. Ronde | 17.10.2021 | HNK Šibenik | - | Hajduk Split | 2:0 | ||||
| 13. Ronde | 22.10.2021 | HNK Šibenik | - | Slaven Belupo | 1:1 | ||||
| 15. Ronde | 07.11.2021 | HNK Šibenik | - | HNK Rijeka | 0:1 | ||||
| 19. Ronde | 12.12.2021 | NK Osijek | - | HNK Šibenik | 3:1 | ||||
| 20. Ronde | 18.12.2021 | HNK Gorica | - | HNK Šibenik | 2:3 |
Colombia