 |
 |
|
|
| U | Flamurtari Vlorë | - | FK Vllaznia | 1:2 | ||
| R | FK Vllaznia | - | Flamurtari Vlorë | 1:0 | ||
| U: 26.01.2022 13:45 | R: 10.02.2022 13:45 | Winnaars: FK Vllaznia | ||||
| U | Egnatia Rrogozhine | - | KF Laçi | 1:1 | ||
| R | KF Laçi | - | Egnatia Rrogozhine | 3:2 d.p. | ||
| U: 26.01.2022 13:45 | R: 10.02.2022 13:45 | Winnaars: KF Laçi | ||||
| U | KF Skënderbeu | - | KF Teuta Durrës | 0:1 | ||
| R | KF Teuta Durrës | - | KF Skënderbeu | 1:0 (1:0) | ||
| U: 27.01.2022 14:25 | R: 09.02.2022 16:45 | Winnaars: KF Teuta Durrës | ||||
| U | Dinamo Tiranë | - | FK Partizani | 1:1 | ||
| R | FK Partizani | - | Dinamo Tiranë | 1:0 | ||
| U: 27.01.2022 16:45 | R: 10.02.2022 18:00 | Winnaars: FK Partizani | ||||
