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| 20.11.2021 | 16:00 | Aubagne FC | - | AS Monaco B | 4:1 (1:0) | |
| 17:00 | GOAL FC | - | FC Martigues | 1:1 (1:1) | ||
| 18:00 | Étoile FC | - | GFA Rumilly Vallières | 1:0 (0:0) | ||
| 18:00 | Jura Sud | - | Lyon-La Duchère | 2:5 (0:2) | ||
| 18:00 | Olympique Marseille B | - | Hyères FC | 1:3 (0:0) | ||
| 18:00 | Olympique Lyonnais B | - | RC Grasse | 1:0 (1:0) | ||
| 18:00 | SC Toulon | - | AS Saint-Priest | 0:1 (0:1) | ||
| 18:00 | Marignane Gignac FC | - | Louhans-Cuiseaux | 2:2 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
GOAL FC | 12 | 7 | 3 | 2 | 21:9 | 12 | 24 |
| 2 |
|
Aubagne FC | 12 | 7 | 2 | 3 | 22:15 | 7 | 23 |
| 3 |
|
RC Grasse | 12 | 7 | 2 | 3 | 14:9 | 5 | 23 |
| 4 |
|
Louhans-Cuiseaux | 12 | 5 | 5 | 2 | 17:11 | 6 | 20 |
| 5 |
|
Olympique Lyonnais B | 12 | 5 | 4 | 3 | 15:14 | 1 | 19 |
| 6 |
|
Jura Sud | 12 | 4 | 4 | 4 | 17:16 | 1 | 16 |
| 7 |
|
Étoile FC | 12 | 4 | 4 | 4 | 12:12 | 0 | 16 |
| 8 |
|
Lyon-La Duchère | 12 | 4 | 3 | 5 | 15:16 | -1 | 15 |
| 9 |
|
FC Martigues | 12 | 3 | 6 | 3 | 10:14 | -4 | 15 |
| 10 |
|
SC Toulon | 12 | 3 | 6 | 3 | 11:10 | 1 | 15 |
| 11 |
|
GFA Rumilly Vallières | 12 | 4 | 3 | 5 | 12:14 | -2 | 15 |
| 12 |
|
Hyères FC | 12 | 3 | 5 | 4 | 11:13 | -2 | 14 |
| 13 |
|
AS Monaco B | 12 | 4 | 2 | 6 | 13:17 | -4 | 14 |
| 14 |
|
Marignane Gignac FC | 12 | 3 | 3 | 6 | 12:16 | -4 | 12 |
| 15 |
|
AS Saint-Priest | 12 | 3 | 1 | 8 | 11:18 | -7 | 10 |
| 16 |
|
Olympique Marseille B | 12 | 3 | 1 | 8 | 11:20 | -9 | 10 |
| Promotie | |
| Degradatie |
