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| U | SS Cosmos | - | SS Virtus | 0:1 (0:1) | ||
| R | SS Virtus | - | SS Cosmos | 1:1 (0:1, 0:1) n.v. | ||
| U: 04.10.2022 20:45 | R: 19.10.2022 20:45 | Winnaars: SS Virtus | ||||
| U | FC Domagnano | - | AC Libertas | 0:2 (0:0) | ||
| R | AC Libertas | - | FC Domagnano | 6:2 (3:1) | ||
| U: 04.10.2022 20:45 | R: 19.10.2022 20:45 | Winnaars: AC Libertas | ||||
| U | FC Fiorentino | - | SP La Fiorita | 0:5 (0:2) | ||
| R | SP La Fiorita | - | FC Fiorentino | 3:1 (2:0) | ||
| U: 04.10.2022 20:45 | R: 18.10.2022 20:45 | Winnaars: SP La Fiorita | ||||
| U | SC Faetano | - | SS Murata | 3:1 (1:1) | ||
| R | SS Murata | - | SC Faetano | 4:0 (2:0) | ||
| U: 05.10.2022 20:45 | R: 18.10.2022 20:45 | Winnaars: SS Murata | ||||
| U | SS San Giovanni | - | SS Folgore/Falciano | 0:0 (0:0) | ||
| R | SS Folgore/Falciano | - | SS San Giovanni | 3:2 (1:0, 2:2) n.v. | ||
| U: 05.10.2022 20:45 | R: 18.10.2022 20:45 | Winnaars: SS Folgore/Falciano | ||||
| U | SP Tre Penne | - | SS Pennarossa | 0:0 (0:0) | ||
| R | SS Pennarossa | - | SP Tre Penne | 1:4 (0:2) | ||
| U: 05.10.2022 20:45 | R: 19.10.2022 20:45 | Winnaars: SP Tre Penne | ||||
| U | AC Juvenes/Dogana | - | SP Cailungo | 2:1 (0:1) | ||
| R | SP Cailungo | - | AC Juvenes/Dogana | 1:1 (0:0) | ||
| U: 05.10.2022 20:45 | R: 19.10.2022 20:45 | Winnaars: AC Juvenes/Dogana | ||||
