| 1. Ronde | 08.01.2022 | Club Tijuana [] | - | Club León [] | 3:2 | ||||
| 3. Ronde | 22.01.2022 | Club Tijuana [] | - | Atlético San Luis [] | 5:0 | ||||
| 4. Ronde | 29.01.2022 | UANL Tigres [] | - | Club Tijuana [] | 2:0 | ||||
| 12. Ronde | 26.03.2022 | Club Tijuana [] | - | UANL Tigres [] | 3:1 | ||||
| 15. Ronde | 20.04.2022 | Club Tijuana [] | - | Santos Laguna [] | 4:1 |
Mexico