| 2. Ronde | 29.08.2021 | Genoa CFC | - | SSC Napoli | 1:2 | ||||
| 3. Ronde | 11.09.2021 | SSC Napoli | - | Juventus | 2:1 | ||||
| 4. Ronde | 20.09.2021 | Udinese Calcio | - | SSC Napoli | 0:4 | ||||
| 5. Ronde | 23.09.2021 | Sampdoria | - | SSC Napoli | 0:4 | ||||
| 6. Ronde | 26.09.2021 | SSC Napoli | - | Cagliari Calcio | 2:0 | ||||
| 12. Ronde | 07.11.2021 | SSC Napoli | - | Hellas Verona | 1:1 | ||||
| 16. Ronde | 04.12.2021 | SSC Napoli | - | Atalanta | 2:3 | ||||
| 17. Ronde | 12.12.2021 | SSC Napoli | - | Empoli FC | 0:1 | ||||
| 18. Ronde | 19.12.2021 | AC Milan | - | SSC Napoli | 0:1 | ||||
| 19. Ronde | 22.12.2021 | SSC Napoli | - | Spezia Calcio | 0:1 | ||||
| 25. Ronde | 12.02.2022 | SSC Napoli | - | Inter | 1:1 | ||||
| 26. Ronde | 21.02.2022 | Cagliari Calcio | - | SSC Napoli | 1:1 | ||||
| 27. Ronde | 27.02.2022 | Lazio | - | SSC Napoli | 1:2 | ||||
| 28. Ronde | 06.03.2022 | SSC Napoli | - | AC Milan | 0:1 |  |
|||
| 34. Ronde | 24.04.2022 | Empoli FC | - | SSC Napoli | 3:2 |
Frankrijk