| 14. Ronde | 05.11.2021 | AS Trenčín | - | MFK Zemplín Michalovce | 4:2 | ||||
| 16. Ronde | 27.11.2021 | AS Trenčín | - | FC DAC 1904 | 0:1 | ||||
| 17. Ronde | 04.12.2021 | ŠKF Sereď | - | AS Trenčín | 4:2 | ||||
| 18. Ronde | 11.12.2021 | AS Trenčín | - | MŠK Žilina | 1:3 |  |
|||
| 19. Ronde | 18.12.2021 | FK Senica | - | AS Trenčín | 1:0 | ||||
| 20. Ronde | 12.02.2022 | AS Trenčín | - | FK Pohronie | 3:0 | ||||
| 21. Ronde | 19.02.2022 | Spartak Trnava | - | AS Trenčín | 0:0 | |
|||
| 22. Ronde | 26.02.2022 | AS Trenčín | - | Tatran Liptovský Mikuláš | 2:2 | |
Slowakije