| 3. Ronde | 07.08.2021 | FK Biolog Novokubansk | - | FK Legion Dynamo Makhachkala | 0:0 | ||||
| 4. Ronde | 15.08.2021 | FK Mashuk KMV | - | FK Biolog Novokubansk | 2:0 | ||||
| 5. Ronde | 18.08.2021 | FK Biolog Novokubansk | - | Spartak Nalchik | 1:0 | ||||
| 6. Ronde | 29.08.2021 | FK Chayka | - | FK Biolog Novokubansk | 2:1 | ||||
| 8. Ronde | 08.09.2021 | FK Druzhba | - | FK Biolog Novokubansk | 1:1 |  |
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| 11. Ronde | 26.09.2021 | FK Biolog Novokubansk | - | Forte Taganrog | 0:0 | |
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| 12. Ronde | 03.10.2021 | FK Dinamo Makhachkala | - | FK Biolog Novokubansk | 2:0 |
Georgië
Rusland