| 4. Ronde | 28.08.2021 | FC Alverca [A-jun] | - | Vitória Setúbal [A-jun] | 6:1 | ||||
| 2. Ronde | 04.09.2021 | Vitória Setúbal [A-jun] | - | União Leiria [A-jun] | 4:3 | ||||
| 5. Ronde | 11.09.2021 | Vitória Setúbal [A-jun] | - | Amora FC [A-jun] | 2:2 | ||||
| 6. Ronde | 18.09.2021 | CD Nacional [A-jun] | - | Vitória Setúbal [A-jun] | 3:2 | ||||
| 15. Ronde | 01.12.2021 | Vitória Setúbal [A-jun] | - | FC Alverca [A-jun] | 0:4 | ||||
| 19. Ronde | 08.01.2022 | Vitória Setúbal [A-jun] | - | Os Belenenses [A-jun] | 2:1 | ||||
| 18. Ronde | 19.01.2022 | SL Benfica [A-jun] | - | Vitória Setúbal [A-jun] | 0:0 | ||||
| 22. Ronde | 29.01.2022 | SG Sacavenense [A-jun] | - | Vitória Setúbal [A-jun] | 2:3 |
Portugal