| 6. Ronde | 31.07.2022 | Santos Laguna [U18] | - | Atlas Guadalajara [U18] | 2:0 | ||||
| 1. Ronde | 03.08.2022 | Santos Laguna [U18] | - | CF Monterrey [U18] | 5:2 | ||||
| 8. Ronde | 14.08.2022 | UANL Tigres [U18] | - | Santos Laguna [U18] | 0:0 | ||||
| 10. Ronde | 21.08.2022 | Pumas UNAM [U18] | - | Santos Laguna [U18] | 2:0 | ||||
| 16. Ronde | 25.08.2022 | Club Tijuana [U18] | - | Santos Laguna [U18] | 1:1 | ||||
| 12. Ronde | 03.09.2022 | CF Pachuca [U18] | - | Santos Laguna [U18] | 3:1 | ||||
| 4. Ronde | 22.09.2022 | Deportivo Toluca [U18] | - | Santos Laguna [U18] | 4:0 |
Mexico