| 3. Ronde | 01.08.2021 | Zenit Izhevsk | - | Zvezda Perm | 0:4 | ||||
| 4. Ronde | 07.08.2021 | Lada Tolyatti | - | Zenit Izhevsk | 2:1 |  |
|||
| 5. Ronde | 15.08.2021 | FK Chelyabinsk | - | Zenit Izhevsk | 1:0 | |
|||
| 6. Ronde | 21.08.2021 | Zenit Izhevsk | - | FK Ural 2 | 1:3 | ||||
| 7. Ronde | 29.08.2021 | Zenit Izhevsk | - | FK Amkar Perm | 0:1 | ||||
| 8. Ronde | 05.09.2021 | Nosta Novotroitsk | - | Zenit Izhevsk | 1:0 | ||||
| 11. Ronde | 26.09.2021 | Zenit Izhevsk | - | FK Tyumen | 0:4 | |
|||
| 12. Ronde | 30.09.2021 | Zenit Izhevsk | - | Torpedo Miass | 0:1 |  |
|||
| 15. Ronde | 17.10.2021 | FK Orenburg 2 | - | Zenit Izhevsk | 2:2 | ||||
| 16. Ronde | 23.10.2021 | Zenit Izhevsk | - | FK Orenburg 2 | 1:1 | ||||
| 17. Ronde | 31.10.2021 | Spartak Tuymazy | - | Zenit Izhevsk | 4:0 | ||||
| 18. Ronde | 04.11.2021 | Volga Ulyanovsk | - | Zenit Izhevsk | 0:1 | ||||
| 19. Ronde | 09.11.2021 | Torpedo Miass | - | Zenit Izhevsk | 1:2 | ||||
| 20. Ronde | 14.11.2021 | FK Tyumen | - | Zenit Izhevsk | 3:0 |
Rusland